MF7Q8

Prompt

1.14.99.20

Oxidoreductases. Acting on paired donors, with incorporation or reduction of molecular oxygen. The oxygen incorporated need not be derived from O2. Miscellaneous. phylloquinone monooxygenase (2,3-epoxidizing).

AI Generated Sequence

170 AAs
MATPTPRWERVARLALCLAGLALSLYALHVERARARDADYRALCDVGTAISCSAVFSSRWGRGFGLVGSIFGADSALNQPNSVYGLIFYLLQLGLGLTASAWAALLLMTSSIVSVAGSLYLAYILAFVLGEFCIVCVSTYALNFALLLISYRRLVYLNEAWKQQLQPKQH

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT85.8
NLMSIM90.0
AACOMP88.1
Seqdif (SeqID)26.1 (XP_004557496.1)
Structdif (F-Target)10.7 (6wvh A)

ProtNLM

NameScore
Vitamin-K-epoxide reductase (warfarin-sensitive)0.533
1.17.4.40.440
VKc domain-containing protein0.011
Vitamin K epoxide reductase complex subunit 10.003
VKORL protein0.002
Ribonucleoside-diphosphate reductase large subunit0.001
Designed by MP, using an AMD MI250 GPU