MEYS2

Prompt

1.14.99.69

Oxidoreductases. Acting on paired donors, with incorporation or reduction of molecular oxygen. The oxygen incorporated need not be derived from O2. Miscellaneous. tRNA 2-(methylsulfanyl)-N(6)-isopentenyladenosine(37) hydroxylase.

AI Generated Sequence

297 AAs
MSDPYRVLLYYKYTPIEDPAAFRADHLAFCKSLGLKGRILVAEEGINGTVSGTYEQTQKYMDWVHSLPGFADLVFKIDEEGHHAFPKMHVRYRKEIVTFGLPENIDPNLETGTHLKPKEFWEAILDEDTVIVDARNDYEFDLGHFRGAIRPDIKNFRELPEWVRDNKEKFLDKKVLTYCTGGIRCEKFSGWMVREGFEDVYQLHGGIATYGKDPEVQGELWDGSCYVFDERISVPINQVDHVIVGKDYFDGTPAEEYVNCANPECNRQILACEENEEKYRGCSTPECAVPAAVAAAA

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT93.9
NLMSIM70.0
AACOMP91.8
Seqdif (SeqID)24.9 (WP_314828837.1)
Structdif (F-Target)12.7 (4f67 A)

ProtNLM

NameScore
1.14.-.-0.368
TRNA hydroxylation protein O0.332
TRNA uridine(34) hydroxylase0.293
Rhodanese domain-containing protein0.001
Rhodanese-related sulfurtransferase0.001
Sulfurtransferase0.000
Designed by MP, using an AMD MI250 GPU