MEVQV

Prompt

1.13.11.17

Oxidoreductases. Acting on single donors with incorporation of molecular oxygen (oxygenases). The oxygen incorporated need not be derived from O2. With incorporation of two atoms of oxygen. indole 2,3-dioxygenase.

AI Generated Sequence

343 AAs

MLPPLPLLPDYGVSTEHGFLPDTPPLTRLPDPYYAPWEAIVANLPQLIISRRLRGVVDRMPVLSTAVLHTEAEWRRAYVVLAFMAHGYIWGGDGPVERLPAAISVPLLEVSAHLGLPPVLTYAAVCLANWRPVFPDAPIDYLDNIATLNTFTGSRDESWFYLVSVAIEARGAPILPLMLTAIDAARAGDAATVTECLRHFAERIDGLGTLLERMHEHCDPVHFYHRIRPFLAGSKNMAEAGLPNGVVYEDGSGGTEYRQFSGGSNAGQSLIQHFDVVLGVEHRPTGEKRAAEEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	92.9
NLMSIM	85.0
AACOMP	84.2
Seqdif (SeqID)	23.9 (KAJ9156605.1)
Structdif (F-Target)	23.0 (8abx A)

ProtNLM

Name	Score
Indoleamine 2,3-dioxygenase	0.384
Indoleamine 2,3-dioxygenase subfamily	0.203
Indoleamine 2,3-dioxygenase family protein	0.079
Indoleamine 2,3-dioxygenase alpha type	0.030
Indoleamine 2,3-dioxygenase 1	0.028
Indoleamine 2,3-dioxygenase,	0.024