MEU38

Prompt

1.14.19.55

Oxidoreductases. Acting on paired donors, with incorporation or reduction of molecular oxygen. The oxygen incorporated need not be derived from O2. With oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water. 4-hydroxybenzoate brominase (decarboxylating).

AI Generated Sequence

297 AAs
MKYDQLRDFIELLEKEGKLKRISKEIDPYLEIGTIADRVLEKGGPALLFENVKGYSIPVLMNLFGTIKRVSMGMGQESVEGLREIGKILDFLKEPPPPHGFKDFLDKLPLWKALNIMTPKTVNSAICQEKVYEGDDVLNRLPILQTCWPGDGALYTFGLMHFTKTEKGKRQNLGIYRMQLGDKNLIMHWAIQHRDKAYFKEYAKKHKKLYVAVAFGTDPITYMYAVSPIPLITYESYFAGLLRNTKTEIVCKITCDLEVPASAEIVLEGYIDPEERLPEGPFGDHTGYYSQADYPFK

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT84.6
NLMSIM65.0
AACOMP91.2
Seqdif (SeqID)39.5 (WP_313859483.1)
Structdif (F-Target)11.6 (5m1d A)

ProtNLM

NameScore
Menaquinone biosynthesis decarboxylase0.629
UbiD family decarboxylase0.206
Menaquinone biosynthesis decarboxylase, SCO4490 family0.034
3-octaprenyl-4-hydroxybenzoate decarboxylase0.029
4.1.1.980.018
4.1.1.-0.015
Designed by MP, using an AMD MI250 GPU