MESWR

Prompt

6.3.2.26

Ligases. Forming carbon-nitrogen bonds. Acid--amino-acid ligases.(peptide synthases). N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine synthase.

AI Generated Sequence

499 AAs

MLEELLEQPEQRLSRLRTVLLGGEALPPELAERWRQLLPEARLLNLYGPTEATVWTTWYPVTPELPEEGRSIPIGRPIPNTRVYVLDEQLQPVPVGVVGELYIGGQGVARGYLNRPELTAERFVPDPFGPEGSRMYRTGDLARYLPDGTLEFLGRLDHQVKIRGFRIELGEIESALQQHPGVKQAVVVAREDRPGDKQLVAYLVPEGGEVPLSPEQLRQHLAEKLPEAVMPAVFVTLDALPLTPNGKVDRRALPAPEFQSRSEYVAPRTELEQQLAQIWAEVLGVERVGVHDFNLFDLTLVQNLANQLLGLLEQAVADPEQRIGELPLLPEEERQQLLGEWNNTAADYPEQTCLHQLFERQVARTPDAVAVVFEGQSLTYRELNQRANQLAHRLRQLGVGPERLVGVCLERSLEMVVGLLGVLKAGGAYVPLDPEYPAERLGYMLEDSGVRLVLTQESLRERLPEGVEVVCLDDEWEVASGENPNLPVTPHDLAYVIYT

Ligand/Cofactor

ATP

C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O)N

Validation Metrics

PLDDT	82.4
NLMSIM	65.0
AACOMP	88.1
Seqdif (SeqID)	50.0 (WP_223756799.1)
Structdif (F-Target)	9.0 (6eby D)

ProtNLM

Name	Score
Amino acid adenylation domain-containing protein	0.347
Non-ribosomal peptide synthetase	0.185
Carrier domain-containing protein	0.110
AMP-binding protein	0.061
AMP-binding enzyme	0.018
Linear gramicidin synthase subunit D	0.017