MECTN

Prompt

3.5.4.3

Hydrolases. Acting on carbon-nitrogen bonds, other than peptide bonds. In cyclic amidines. guanine deaminase.

AI Generated Sequence

298 AAs
MTTAFRGALLHFSNDPSGSIDESAYLIFEDGGLLIDNGKIRAIGPYASLKAVPGISIVDYHKHLILTPGFIDTHVHYPQTNIIASYGPQLLPWLNTYTFPAEKAAFDPKYAEKVAKFFVDELVRNGTTTALVFSTIHKGSVDAFFEAAEKRGMRMIVGKVMMDRNAPEGLRDTAQSGYDESKALIERWHSKGRLHYAITPRFAPTSTPEQMALAGKLAAEYPDLYMQTHLSENKDEIEWVKELFPEGRDYLDVYDVFGLLKRESVFAHGIHLDDEERRRLSETGASIAFCPTNLFVGS

Ligand/Cofactor

guanine

C1=NC2=C(N1)C(=O)NC(=N2)N

Validation Metrics

PLDDT93.5
NLMSIM90.0
AACOMP95.4
Seqdif (SeqID)35.3 (WP_131651053.1)
Structdif (F-Target)4.2 (6ohb D)

ProtNLM

NameScore
3.5.4.30.403
Guanine deaminase0.305
Guanine aminohydrolase0.149
Guanase0.108
Amidohydro-rel domain-containing protein0.014
Adenine deaminase0.002
Designed by MP, using an AMD MI250 GPU
EC Repo - MECTN | 310.ai