MEAG3

Prompt

7.2.2.8

Translocases. Catalysing the translocation of inorganic cations. Linked to the hydrolysis of a nucleoside triphosphate. P-type Cu(+) transporter.

AI Generated Sequence

234 AAs
MTTTILKVEGMTCGHCVARIEKGVGKLPGVKSVHVDLATGTATVEFDPATVTPEQIREAIEDAGYDAEVLETEHLDGVDLVVSGNVAEVEALVKGEVGENVDLALSTESRVKVFDPDVIGPRAIVEAIEQAGYNAVVAKNVQDTAHELEHIEIEQWKRKFLIVSVFLAMPVLMGVMLPDGVSHGVTLIECGIISLNLIFALVCTPVQFMGGRFYIEAAYKALKEGATNMDVLVA

Ligand/Cofactor

ATP

C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O)N

Validation Metrics

PLDDT81.8
NLMSIM85.0
AACOMP89.8
Seqdif (SeqID)60.1 (GFN81620.1)
Structdif (F-Target)3.1 (3dxs X)

ProtNLM

NameScore
Heavy metal translocating P-type ATPase0.292
Copper chaperone CopZ0.158
Copper chaperone0.134
HMA domain-containing protein0.066
Heavy metal transport/detoxification protein0.035
Cation-translocating P-type ATPase0.031
Designed by MP, using an AMD MI250 GPU