MEA6K

Prompt

1.5.1.36

Oxidoreductases. Acting on the CH-NH group of donors. With NAD(+) or NADP(+) as acceptor. flavin reductase (NADH).

AI Generated Sequence

474 AAs

MSERPHPVVVVGGLGAGLALARRLGRRDARITLVDRNSFHTFQPPLLHVATGRLSARSVDPALEARFARRHNVRLLQEEVAGIDLATRTVRAADGEELAYDRLVIALGGESNFFGIPGLERHAPGLKTIEDALAIRRHLLANFARAEPLTDPERRARLLTFVIVGGGPTGVEIAGELHEMADRTLPYDFPRIDRREARIHLVEAGDRILPAFADRLSAYAERQLRELGVEVLTGARVADCAEHGVRTRDGEEIAARTMVWAAGVASPAVARELGAEQTRRRQLVVDPHLRTVPGDEVFAVGDCASAVPGGTRGHLPGVAQAAQQMGEYVARNIAARMAGRPLPPFRYRDHGSLATIGRNAAVVDLGKFRLSGFFAEWLWWAVHLAFLVSFRNRLRVVFNWAASYMTWDRSLRLITGRQYRHEREAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Ligand/Cofactor

FAD

CC1=CC2=C(C=C1C)N(C3=NC(=O)NC(=O)C3=N2)CC(C(C(COP(=O)(O)OP(=O)(O)OCC4C(C(C(O4)N5C=NC6=C(N=CN=C65)N)O)O)O)O)O

Validation Metrics

PLDDT	90.3
NLMSIM	75.0
AACOMP	83.7
Seqdif (SeqID)	48.0 (WP_143879742.1)
Structdif (F-Target)	6.5 (5na1 A)

ProtNLM

Name	Score
NADH dehydrogenase	0.248
NAD(P)/FAD-dependent oxidoreductase	0.234
FAD-dependent oxidoreductase	0.179
Pyridine nucleotide-disulfide oxidoreductase	0.067
1.6.99.3	0.061
NADH dehydrogenase FAD-containing subunit	0.043