ME8SC

Prompt

1.6.99.1

Oxidoreductases. Acting on NADH or NADPH. With other acceptors. NADPH dehydrogenase.

AI Generated Sequence

290 AAs

MAARRLLSRGLSVRLAGARVTEVSDGVVTLKDGAEIPTDLLVWATGVQAPRLAKELGLEQDRNRQLLVDPNLQVSGYDNVYAVGYTSTNFGIPGVAEHCFFLKDVEQAQRLRHRIMNCFEKASLPTSDEERKKLLTFAIVGGGPTGVELSGELHDLVEDLSKYFPKINPNELSITLIEAGPRILSAMPEKISAYAEEKLSKRGVDVLLGTRVKSVKDGKVYTFKDGSEIPTDLLVWSTGVQAPDVLKELGLELDRNGRQLVVEPLQLRGVDNYVDWIGGGIGRILGALVR

Ligand/Cofactor

NADH

C1C=CN(C=C1C(=O)N)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O

Validation Metrics

PLDDT	79.2
NLMSIM	70.0
AACOMP	93.2
Seqdif (SeqID)	49.5 (XP_012752861.1)
Structdif (F-Target)	29.9 (6ynz 3)

ProtNLM

Name	Score
Pyr_redox_2 domain-containing protein	0.726
NADH dehydrogenase	0.042
FAD/NAD(P)-binding domain-containing protein	0.025
1.6.5.3	0.012
Pyridine nucleotide-disulfide oxidoreductase family protein	0.009
1.6.99.3	0.008