MDTU6

Prompt

1.2.1.61

Oxidoreductases. Acting on the aldehyde or oxo group of donors. With NAD(+) or NADP(+) as acceptor. 4-hydroxymuconic-semialdehyde dehydrogenase.

AI Generated Sequence

500 AAs

MTTKNLFINGEFVNSSGRTFPVINPVNGEVIGQVHEAGAEEVDAAVKAARKAFDGPWSKMTGVDRARILYKIADDIEKQFDDFIAAEITDTGKTYAEAKAFDVIRCAQNLDFFSEAVKKLPGESVMSLDDDDPGHLANYVVRKPVGVVGIICPWNFPLLMLTKGIAPALACGNTVVVKPSEFTPLTAVELAEIMKDAGLDPGVYNVVHGFGPEAGEFLVKHPKVDAITFTGSTGVGKLIMEAAGKSLKRVSLELGGKNAVIVADDADLDKAIEGSLWGIFTNSGQVCLGTERIYVERSIFDEFVAGLKKEAEKLKIGDPGMDETNFGPLISQKHRDKVLSYFKIAKDEGATIITGGGVPEGLDAKGNFIAPTVFTGVTDDAKMVKEEIFGPVCHVIKFDTEEEAVKLANDTPYGLATSVFTQNLKRIHFVRNQLEVGMVWINSWFLLRTRTPFGGVKMSGIGREGGVHSLDEFTEVKNVCVKLGGKDKKKKKKKKKKKKK

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	95.9
NLMSIM	70.0
AACOMP	90.8
Seqdif (SeqID)	40.7 (WP_058092969.1)
Structdif (F-Target)	2.5 (7bzv B)

ProtNLM

Name	Score
Aldehyde dehydrogenase	0.414
Betaine-aldehyde dehydrogenase	0.136
2-hydroxymuconic semialdehyde dehydrogenase	0.107
1.2.1.85	0.082
1.2.1.8	0.057
Aldehyde dehydrogenase family protein	0.041