MDTGB

Prompt

1.6.1.3

Oxidoreductases. Acting on NADH or NADPH. With NAD(+) or NADP(+) as acceptor. NAD(P)(+) transhydrogenase.

AI Generated Sequence

268 AAs

MAAALHEALVHSLAKYGLKINPELNISLIDAAGRILPAMFPKISTYAEEEFKKRGVDVLRTGRMVKSVAEGTVTTKDGTEIPTRTLVWSTGVAAPVLMKDLAPLTERGAQLLVDENLQLSGVDPNYVGFTGVYNHCMFLKDLSEAQRIRHQIMNCFEKASFITDEEKRKLLTFAVVGGGPTGVEFAGELHDMVTQSLKKYGYKINPENIKISLIDAAGRILPAMFKKISTYAENEFLKRGVDVLLTGRMVTKVEDGTVVTKDGTEIPT

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	75.8
NLMSIM	85.0
AACOMP	94.0
Seqdif (SeqID)	49.7 (AFN53706.1)
Structdif (F-Target)	34.8 (5yjw 2)

ProtNLM

Name	Score
Pyr_redox_2 domain-containing protein	0.816
NADH dehydrogenase	0.028
Pyridine nucleotide-disulfide oxidoreductase	0.026
FAD-dependent oxidoreductase	0.024
FAD-dependent pyridine nucleotide-disulfide oxidoreductase	0.014
FAD/NAD(P)-binding domain-containing protein	0.008