MDNZN

Prompt

1.1.1.95

Oxidoreductases. Acting on the CH-OH group of donors. With NAD(+) or NADP(+) as acceptor. phosphoglycerate dehydrogenase.

AI Generated Sequence

500 AAs

MKILVSDHLSEAGLALLKDAGFEVDVETGLPRDELLAKIGDYDALIVRSGTKVTAEVIEAAGNLKVIGRAGVGVDNVDLPAATKRGILVMNAPEGNTISAAEHTFAMMLALARNIPQADASVKAGEWDRKSFVGVELYGKTLGIIGLGRIGSEVARRAKAMGMHVIAYDPYVSPERAAQLGVEKVSLDELLAKSDFITVHLPKTPETRHMINAEQFAKMKPGVRIINCARGGIVDEAALYDAIKSGHVAGAALDVFETEPCTDSPLLELPNVICTPHLGASTKEAQENVGIDVAEQVVRYLKGEPVRNAVNMPSVGAEVMEQVKPYLDLAEKMGHLAAQLAGGPVEKVSIEYRGEIAEYDTKPLTTAALKGLLSPAIAENVNMVNAPLLAKERGIQITEKKHESSENYRNLITVRATTSDGSRSVAGTLFGKGVPRIVKINGFEVDVRPEGHMLIHHNKDRPGMIGKVGTILGENNVNIASMQVGREVGGETAIMLLSVD

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	90.1
NLMSIM	85.0
AACOMP	93.6
Seqdif (SeqID)	38.8 (MCL6614819.1)
Structdif (F-Target)	2.6 (6plf B)

ProtNLM

Name	Score
D-3-phosphoglycerate dehydrogenase	0.551
1.1.1.95	0.440
Phosphoglycerate dehydrogenase	0.005
1.1.1.399	0.001
2-oxoglutarate reductase	0.001
Superoxide dismutase	0.000