MDGHA

Prompt

7.1.1.12

Translocases. Catalysing the translocation of hydrons. Hydron translocation or charge separation linked to oxidoreductase reactions. succinate dehydrogenase (electrogenic, proton-motive force generating).

AI Generated Sequence

130 AAs
MAPKTGKPLSPHLTYRGKEGMWSWVLHRITGVTIFFFLFVHLLDLALVRVSPEAYDAVMATYKTPMFGLMEVGLVAAILFHAFNGLRIILVDFWAKGKKYQKVMLWGVVGFWLVTMIPGFPRVLGNVFGG

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT78.8
NLMSIM95.0
AACOMP88.3
Seqdif (SeqID)29.5 (WP_281272131.1)
Structdif (F-Target)14.1 (6lum C)

ProtNLM

NameScore
Succinate dehydrogenase, cytochrome b556 subunit0.660
Succinate dehydrogenase subunit C0.240
Succinate dehydrogenase 2 membrane subunit SdhC0.019
Succinate dehydrogenase/fumarate reductase, cytochrome b subunit0.018
Succinate dehydrogenase/Fumarate reductase transmembrane subunit0.008
Succinate dehydrogenase0.008
Designed by MP, using an AMD MI250 GPU