MDFT1

Prompt

1.7.1.7

Oxidoreductases. Acting on other nitrogenous compounds as donors. With NAD(+) or NADP(+) as acceptor. GMP reductase.

AI Generated Sequence

398 AAs

MRIENDVKLDFKDVLFRPKRSTLKSRSEVDLERTFTRFHSGKTYTGIPIIAANMDTVGTFEMAKVLAEHGIMTALHKHYTVEEWKAFVAKNPEVLHHYVAVSGTGSDQDFQKLTDIVKGHPQIKFICLDVANGYSHVFVEFVELVRKAFPHKTIMAGNVVTGEMTEELILSGADIIKVGIGPGSVCTTRKVGAGVYPQLSAVIECADAAHGLGGRIISDGGCTCPGDVAKAFGAGADFVMLGGMLAGHDESGGEIMDVNGKKFKMFYGMSSDTAMKKHAGGVAEYRASEGKTVEVPFRGPVEETIKEILGGVRSTCTYVGAAKLKELSKRTTFIRVTQEHNMVFGKGEGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	84.1
NLMSIM	90.0
AACOMP	83.0
Seqdif (SeqID)	21.9 (KAG8596088.1)
Structdif (F-Target)	2.6 (2bwg A)

ProtNLM

Name	Score
GMP reductase	0.391
1.7.1.7	0.218
Guanosine 5'-monophosphate oxidoreductase	0.190
Guanosine monophosphate reductase	0.104
GMPR	0.082
GMP reductase 1	0.000