MDFCR

Prompt

1.14.18.6

Oxidoreductases. Acting on paired donors, with incorporation or reduction of molecular oxygen. The oxygen incorporated need not be derived from O2. With another compound as one donor, and incorporation of one atom of oxygen. 4-hydroxysphinganine ceramide fatty acyl 2-hydroxylase.

AI Generated Sequence

265 AAs
MLSNLLSEFWNAYYLMDDNAYIATIGSFLLHEVVYFFLRGLPFWIIDRIYPFLKYKIQKDKPITPNEQWKCFKTVLFSHFTVELPLQWVAHPMTEYFGMRYPLPLPSWKMMLLQILFFFVIEDTQYYWMHRAMHTKYLYKHIHKVHHEYSAPYGLAAEYAHPLEGILLDFATPIGPLLMKCHLLLTMMYWTVRLLFTIEDHSGYDIPWSLHHLIPFFAGGDYHDIHHQFYEKGKYNYAQSFFTWMDKLFGTTKPAKYKKIEKKKK

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT89.1
NLMSIM62.7
AACOMP87.3
Seqdif (SeqID)48.7 (KAK5095721.1)
Structdif (F-Target)51.2 (3ihu B)

ProtNLM

NameScore
Fatty acid hydroxylase domain-containing protein0.627
C-4 methylsterol oxidase0.052
Methylsterol monooxygenase 10.048
1.14.18.90.045
Methylsterol monooxygenase 1-like0.024
Methylsterol monooxygenase 1-10.011
Designed by MP, using an AMD MI250 GPU