MCTI6

Prompt

4.2.1.118

Lyases. Carbon-oxygen lyases. Hydro-lyases. 3-dehydroshikimate dehydratase.

AI Generated Sequence

627 AAs
MKRSIATVSLSGTLPEKLEAIAAAGFDGVEIFENDLLYFDGSPREVRRMCADLGIAITLYQPFRDFEGCREDRRSRNLDRAERKFDLMQELGTDLVLVCSNVTPDAVGDIERLVDDLRELAERAAARGLRIGYEALAWGRHVNTWHDAWEIVRQVDHPNLGLLLDSFHTLSLKGDPGSIAEIPGEKIFFVQMADAPLIAMDVLEWSRHFRCMPGEGELPLTGFMAPIIATGYAGPLSLEIFNDQFRAAPTRANALDGMRSLLLLEEKTRQLLPAEDVPLFMPPPKSVYEGIGFIEFAVDEENGARLGGWLERLGFRKAGQHRSKNVSLLRQGDINLILNAEPYSFAHSFYAAHGPSLCATALRVDDAADAHARAVALKGAPYQGLVGPNEMEIPAVRAPDGGLIYLVDQPSEGRSLYETDFVLDRTAAAAGLARIDHVAQALPAESLDSWVLFYKSLFDFAATDEVELPDPYGLVKSRAIRSTCGAIRLTLNGSENRNTAIGHAIASYFGSGVHHIAFACADIFAEVERAKAAGMPLLDIPLNYYDDLAARFDFDDEFVSELAAYNVLYDRDAGGEFFQVYTRPFEGRFFFEIVQRKNGYAGYGAANIPVRIAAQMAKRGSVAAMKE

Ligand/Cofactor

3-dehydroshikimate

C1C(C(C(=O)C=C1C(=O)O)O)O

Validation Metrics

PLDDT89.7
NLMSIM70.0
AACOMP93.6
Seqdif (SeqID)22.3 (WP_218728508.1)
Structdif (F-Target)13.7 (5hmq C)

ProtNLM

NameScore
4.2.1.1180.405
DSD0.357
3-dehydroshikimate dehydratase0.225
4-hydroxyphenylpyruvate dioxygenase0.001
TIM barrel protein0.000
Sugar phosphate isomerase/epimerase and 4-hydroxyphenylpyruvate domain-containing protein0.000
Designed by MP, using an AMD MI250 GPU
EC Repo - MCTI6 | 310.ai