MCQN7

Prompt

1.14.13.148

Oxidoreductases. Acting on paired donors, with incorporation or reduction of molecular oxygen. The oxygen incorporated need not be derived from O2. With NADH or NADPH as one donor, and incorporation of one atom of oxygen. trimethylamine monooxygenase.

AI Generated Sequence

553 AAs

MAKKVVVVGAGFSGLGAARCLDKLKLPEVEFEVQDRNGGVWTWDPLPEVASSTYESHIISQPIRMTFPDFPFPHWPGAYMNHDEIQKYVDKAKDFELPYDYLVVATGSVNTHFGTPGWKDHCFTLKESGDAQLIRNQIMNLCAAGLHTPENEEKKGLFNFIVGGGHTGVELAGALFDMVKRVLVVGYPNSELDIAITLVEAAPRILSPFDKRSINYAVRNLKKRGVDVWLNTRMVKVTENGLTMKDGKEIPYKTMVWATGVQNAPFLKGLGKELGQRNITLEDNYLRVSGDDKVWAIGDCTNSEVFTNGTLPTVAQVAAQTGTYLGKNFPALLDGKVKEAFHYHDKGLVAPIGWKDALAVLPGLKVSGLFAPFFWQAKWYARLVFSTNRLPLSMDWMLDYIFNRDRMDRFIGGRKKTIVRFDTWMDYVDDLVDKIAKRPDWKELLDKDWVKYEVFGGPKPYQWRLEGFKPGDWEGRAIYDLDTWRLKPLMHRVIGDGKPRPRPAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Ligand/Cofactor

NADH

C1C=CN(C=C1C(=O)N)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O

Validation Metrics

PLDDT	71.3
NLMSIM	65.0
AACOMP	91.6
Seqdif (SeqID)	67.4 (HWA07821.1)
Structdif (F-Target)	10.3 (5kmr C)

ProtNLM

Name	Score
Pyr_redox_2 domain-containing protein	0.527
NAD(P)/FAD-dependent oxidoreductase	0.157
FAD/NAD(P)-binding domain-containing protein	0.075
FAD-dependent pyridine nucleotide-disulfide oxidoreductase	0.045
FAD-dependent oxidoreductase	0.038
Pyridine nucleotide-disulfide oxidoreductase	0.030