MCQI9

Prompt

1.6.1.2

Oxidoreductases. Acting on NADH or NADPH. With NAD(+) or NADP(+) as acceptor. Transferred entry: 7.1.1.1.

AI Generated Sequence

298 AAs

MKNFELAYLPGTDEERARLLSFCVVGGGATGVELAAELYDMVQDDLAKYYPKVKENLKITLIEASPRILATFDEKISKYAEETFARDGIDVLTNSMVKSVEADGVYLKDGKEIPYGMLVWATGVKANPFCKDLAPLDQNRGRQLKVDYWLQVTGLDNIYALGDFIAHGKELGKEFGKLLEEHPELKKLLEEHPELKKLLEEHPELKELLEEHPELKKLLEEHPELKKLLEEHPELKKLLEEHPELKKLLEEHPELKKLLEEHPELKKLLEEHPELKKLLEEHPELKKLLEEHPELKKL

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	80.1
NLMSIM	70.0
AACOMP	81.3
Seqdif (SeqID)	46.4 (KAJ8434116.1)
Structdif (F-Target)	46.5 (4nwz 3)

ProtNLM

Name	Score
Pyr_redox_2 domain-containing protein	0.666
NADH dehydrogenase	0.056
1.6.99.3	0.052
Pyridine nucleotide-disulfide oxidoreductase	0.034
FAD-dependent pyridine nucleotide-disulfide oxidoreductase	0.029
FAD-dependent oxidoreductase	0.029