MC19P

Prompt

1.17.99.11

Oxidoreductases. Acting on CH or CH2 groups. With other acceptors. 3-oxo-Delta(1)-steroid hydratase/dehydrogenase.

AI Generated Sequence

391 AAs

MEHLENQLLLSLTLLLGVAAVFTGLLLYELVPYKGYRHEFSRLGWRVPCRCAWFLQELPSFLVPVALLLARARGESLSLPNRCLLGLFFCHVYQRSLIYPLHIRGGKTPFPVTFALMAFFCIYNGYLQQRYLSHVAEYPESWVTDPRFISGVLLHLLGMWVNIHSDRILRNLRKPGETGYKIPRGGLFEYVSGANYFGEIVEWCGFALCTWSVAGLAFAFLTTVNLGPRAREHHRWYLKKFTDYPKSRKELIPFMFICTPFTGLPFTLLSTTQVFAFLSRWLGGRSSESYWENYSKYPLRPLAFIPLLPPKTPKLFLLLLGGVMSYWSEYVRRWMRRSSSDSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	74.3
NLMSIM	85.0
AACOMP	84.4
Seqdif (SeqID)	41.0 (XP_006875031.1)
Structdif (F-Target)	7.3 (7c83 A)

ProtNLM

Name	Score
S5A_REDUCTASE domain-containing protein	0.270
1.3.1.22	0.226
3-oxo-5-alpha-steroid 4-dehydrogenase	0.217
3-oxo-5-alpha-steroid 4-dehydrogenase (NADP(+))	0.176
SR type 1	0.032
3-oxo-5-alpha-steroid 4-dehydrogenase 1	0.017