MBQE1

Prompt

4.2.1.28

Lyases. Carbon-oxygen lyases. Hydro-lyases. propanediol dehydratase.

AI Generated Sequence

575 AAs
MTDRPRLRSRLWDDGPGDRTAFMYRAWMLPQDYPEELWQGKPVIGIANTWSELSPCNRRHRELAEAVKRGIWAAGGFPIEFPVHSIGENSMRPTAMLDRNLASMDVEEVIRGQPLDGVVLLTGCDKTTPGQLMGAATVDLPAIVVSGGPMLSGWHRGERIGSGTVVWKSRERVAAGEIDEAGFMAAEAGMAPSYGHCNTMGTASTMACVAEALGMSLPGNAAIPAVDRERLQMAYRTGRRIVEMVWEDLRPSDILTKEAFENAIRVNAAIGGSTNAPLHLTAIAGRIGVELTLDDWDRFGRDVPTLVNLKPSGEYLMEDFYHAGGVPAVVRELGDAGLLHGDALTVTGKTIGENLAGAPVYDEDVIRPIDNPLYKESGFAVLRGNLFPNGAVMKPSAISPELLRHTGRAVVFENIDDYHARIDDPELDITEDSVLVLRNCGPKGYPGMAEVGNMGIPPKLLKQGVTDMARISDARMSGTAYGTVILHVAPEAAAGGPLALVRNGDWITLDLARGRLNLLVDDAELAARRAAWEALPVYARGYPQLYIEQGVLQADQGCDFDFLVGLVGHDVPRDH

Ligand/Cofactor

propanediol

CCC(O)O

Validation Metrics

PLDDT82.2
NLMSIM60.0
AACOMP93.2
Seqdif (SeqID)31.6 (WP_225135271.1)
Structdif (F-Target)4.5 (5j83 A)

ProtNLM

NameScore
Dihydroxy-acid dehydratase0.592
4.2.1.90.283
Dihydroxyacid dehydratase0.027
4.2.1.250.025
L-arabonate dehydratase0.016
Dihydroxyacid dehydratase/phosphogluconate dehydratase0.011
Designed by MP, using an AMD MI250 GPU