MBO26

Prompt

1.23.1.2

Oxidoreductases. Reducing C-O-C group as acceptor. With NADH or NADPH as donor. (+)-lariciresinol reductase.

AI Generated Sequence

282 AAs

MKKIVVVGGGFAGVELAGELAKKLGKKDYDITLVDRNNYHTFQPLLHQVATGTIESRSIDEPFRGHLKQRHNFHFQLGEVTDIDREAKKIQLAGVEDYVSYDYLVIGMGSVTNNFGIPGVKEHAIGLKSVEDALKIRHHVLNNFEKAYRLTTDEERKKLLTFAIVGGGATGVELAGELADIVKDLIPDYLPNIDLENMNITLIEAGDRILAAMPEKISAYAHKHLKEMGVEVLTNAMVTSYEGDGVKTKDGKFIETDMTVWATGVKASPVVKALGIETDNRG

Ligand/Cofactor

NADH

C1C=CN(C=C1C(=O)N)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O

Validation Metrics

PLDDT	94.7
NLMSIM	60.0
AACOMP	91.9
Seqdif (SeqID)	51.0 (WP_320705738.1)
Structdif (F-Target)	7.6 (5kmq C)

ProtNLM

Name	Score
FAD-dependent oxidoreductase	0.330
NAD(P)/FAD-dependent oxidoreductase	0.251
NADH dehydrogenase	0.205
Pyridine nucleotide-disulfide oxidoreductase	0.049
1.6.99.3	0.036
Pyr_redox_2 domain-containing protein	0.035