MB75L

Prompt

1.3.1.3

Oxidoreductases. Acting on the CH-CH group of donors. With NAD(+) or NADP(+) as acceptor. Delta(4)-3-oxosteroid 5beta-reductase.

AI Generated Sequence

376 AAs

MATKLKLTNGHKIPLLGLGTWQAPPKGQVLEAVKYAIDAGYRHIDCAFVYQNEHEVGQAIREKIAEGTVKREDLFYCGKLWNTFHPPKLVRPAFEKTLKDLQLDYVDLYIIHFPMAFKPGDDLLPKDENGKIIYSKTDLLATWEAMELCKDAGLVKSIGVSNFNHRQIEMILNKPGLKYKPVVNQVECHPYLTQEKLLEFCQSHGIVITAYSPLGSPRDPSWVNKDSPALLEDPVLKAIAKKHNKTAAQVALRFNIQRGIVVIPKSFNPHRIQENFQVFDFKLSKEEMEAINGYNRNIRFVELMTCVAHPEYPFHDEYIDDPIYAPKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	91.5
NLMSIM	60.0
AACOMP	82.7
Seqdif (SeqID)	25.5 (XP_054137928.1)
Structdif (F-Target)	2.0 (1ry8 B)

ProtNLM

Name	Score
Aldo_ket_red domain-containing protein	0.590
Aldo-keto reductase family 1 member B10	0.031
Aldo-keto reductase family 1 member B1	0.023
AK1BA reductase	0.022
Aldose reductase-like	0.022
Aldo-keto reductase family 1, member B1 (aldose reductase), tandem duplicate 1	0.020