MAWNP

Prompt

1.5.1.37

Oxidoreductases. Acting on the CH-NH group of donors. With NAD(+) or NADP(+) as acceptor. FAD reductase (NADH).

AI Generated Sequence

470 AAs

MSHPHVVLIGGGLEGTGIARDLARRGYDVTLVDRNNFHTTTPLLHHLVAAGRLEPSADIPFLRALARENHVDFLLGEAHEVDRARRMVLLPGDRRLAYDRLVIGLGSTHNFFGIPGLEEHAIGLKDLADATAIRRHLLEAFERAHLETDPARRAALLTFVIVGGGFTGVELAGEIADMVRHLTPYDFPRIDRSAIDVTLVEAGPRILPAFADEISAHAERHLQGMGVEVRLGSRVSECGDHGVVTRDGEVIPADTVVWTAGIAANPFGEAIGVETDRAGRLVVDEHLRTPGDPDIYAVGDCAHFPPDGRPVPPTAQAAKQMGEYLARNIAARMDGRPLAPFHYKDHGSLVAIGRWTAVAELMGKITFGGFAEWLWRMAFHSSFLSRMNRLTVYGDWAAGYMTFDRSIRIITEPRLRAEEHAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	89.9
NLMSIM	85.0
AACOMP	85.9
Seqdif (SeqID)	51.0 (WP_324860069.1)
Structdif (F-Target)	7.1 (5na1 A)

ProtNLM

Name	Score
NAD(P)/FAD-dependent oxidoreductase	0.266
NADH dehydrogenase	0.254
NADH dehydrogenase FAD-containing subunit	0.085
1.6.99.3	0.084
Pyridine nucleotide-disulfide oxidoreductase	0.067
FAD-dependent pyridine nucleotide-disulfide oxidoreductase	0.039