MAPWH

Prompt

4.2.3.5

Lyases. Carbon-oxygen lyases. Acting on phosphates. chorismate synthase.

AI Generated Sequence

416 AAs

MAGNTFGHLFRVTTWGESHGPALGAVVDGCPPGLPLTAADIQAWLDRRRPGQSRFTTQRREPDAVRILSGVFEGRTTGTPIQLMIENTDQRSKDYGDIAQAYRPGHADYAYWQKYGIRDYRGGGRSSARETAARVAAGAVARAVLAELAPGLTITGYVMQIGPHRIDRARFDWAEIDRNPFWCPDAAAAAEWAAYLDGLRKAGDSVGAVVEVVAEGVPAGIGAPVYAKLDTDLAAAMMSINAVKGVEIGEGMAAAALTGSENADEIFMGPDGRPVFLSNHAGGILGGISTGQPVVARFAVKPTSSILTPRQTVTRAGEETEIVTKGRHDPCVGIRAVPVVEAMMACVIADHLLLHRGQTGGRGGRIGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG

Ligand/Cofactor

ATP

C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O)N

Validation Metrics

PLDDT	86.1
NLMSIM	85.0
AACOMP	82.6
Seqdif (SeqID)	15.8 (WP_132545911.1)
Structdif (F-Target)	8.7 (7rca A)

ProtNLM

Name	Score
Chorismate synthase	0.268
4.2.3.5	0.254
CS	0.250
5-enolpyruvylshikimate-3-phosphate phospholyase	0.223
5.4.99.18	0.000
3-dehydroquinate synthase	0.000