MAHUR

Prompt

6.3.1.5

Ligases. Forming carbon-nitrogen bonds. Acid--ammonia (or amine) ligases.(amide synthases). NAD(+) synthase.

AI Generated Sequence

262 AAs
MQAEKVADHIVGWLKDYAANAGMKGFVVGVSGGIDSAVTSTLCAMTGLPLLCVEMPIHQAASQVSRAQEHIDWLKKRFPNVSLAAVDLTPVFDAFKTEVPAVDDEWRLDMALANTRARLRMTTLYYFAGLHGYLVAGTGNKVEDFGVGFYTKYGDGGVDLSPIADLMKSEVYALARELAVPESIQVAAPTDGLWGDDRTDEDQLGASYPELEWAMKAMDEGKTADDFSGREKEVFDIYKRLNRANQHKMIPIPVCEIPEELK

Ligand/Cofactor

ATP

C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O)N

Validation Metrics

PLDDT92.8
NLMSIM95.0
AACOMP94.1
Seqdif (SeqID)23.3 (WP_015481942.1)
Structdif (F-Target)4.2 (3fiu D)

ProtNLM

NameScore
6.3.1.50.511
NH(3)-dependent NAD(+) synthetase0.478
NAD(+) synthase0.003
NAD+ synthase0.001
NAD_synthase domain-containing protein0.001
Ammonia-dependent NAD(+) synthetase0.001
Designed by MP, using an AMD MI250 GPU