MAGCH

Prompt

1.2.1.95

Oxidoreductases. Acting on the aldehyde or oxo group of donors. With NAD(+) or NADP(+) as acceptor. L-2-aminoadipate reductase.

AI Generated Sequence

998 AAs

MTTPDPTSDLDWSGYRGAIQHIFAANAERHPDRPCVVETASSERREFTYRQIDEASNVLAHHLVAAGVERGDVVMIYAYRGVDLVVAVMGVLAAGGTFSVLDPAYPPARQQIYLDVAQPRALVVIEKATQEAGPLSELVRTYIDENLELRTEVPALALRDDGSLTGGALDGQDVLADTQALKAETPGVVVGPDSIPTLSFTSGSEGRPKGVLGRHFSLAYYFDWMAERFGLSENDRFTMLSGIAHDPIQRDIFTPLFLGAQLLVPAKEDIQHERLAEWMREYGATVTHLTPAMGQILVGGATAQFPSLHHAFFVGDILTKRDCRALQLANPAVNVMNSYGTTETQRAVSYYEIPSRSTDPNFLDSMKDVIPAGRGMVDVQLLVVNRNDRTKICAVGEVGEIYVRAGGLAEGYLGLPELNAEKFVTNWFVDPQKWVEKDQANVASKNEPWREFYKGPRDRMYRSGDLGRYTPSGDVECTGRADDQVKIRGFRIELGEIDTHLSQHPLVRENKTLVRRDKFEEPTLVSYIVPDMRKWAEWLESKGRDDDDVSGTSEMGPVYVGLRRYRHLQTDIREHLRTKLPAYAVPTVLVPLVKLPLNPNGKVDKPALPFPDTAQLSAFAASRTSRAQWESLTETERTVARIWAGLIPNVPARTIGPDDSFFDIGGHSLIATQMLFTVRRKWNVDVPMNTIFNAPTLRGFAAEVDRLQSGEDLSAETAAADEAYSEDAKALVEALPAKFPAATEALPSEPTTFLTGATGFLGSYILRDLLERSPDVKVIVHNALVHWVKPYAELRATCQVYGIWQDEWVNSTIDAMNLCANGKPKQLSFVSSTSVLDTDHYVGLSENDLEGSRTGLTTGYGQSKWVSEYLVRRAGKRGLRGTIVRSGYITGDSKTGVTNTDDFLIRMLKGCIQLGSARPNITNTVNMVPVTHVARVVIATHLAPPPASGLNVVHVTGHPRLNFGQFLGALELYGYDVPQVDYLTWKAKLEEYISGVKK

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	77.4
NLMSIM	85.0
AACOMP	96.0
Seqdif (SeqID)	32.6 (XP_001271987.1)
Structdif (F-Target)	6.4 (1amu B)

ProtNLM

Name	Score
Alpha-aminoadipate reductase	0.356
1.2.1.95	0.328
1.2.1.31	0.203
L-aminoadipate-semialdehyde dehydrogenase	0.091
2-oxoglutarate dehydrogenase E1 component	0.001
1.2.1.-	0.001