MAG95

Prompt

1.13.11.53

Oxidoreductases. Acting on single donors with incorporation of molecular oxygen (oxygenases). The oxygen incorporated need not be derived from O2. With incorporation of two atoms of oxygen. acireductone dioxygenase (Ni(2+)-requiring).

AI Generated Sequence

182 AAs
MSTLRIHELTTPDQPLRHSTHLEEIASELYKIGVAFERWHADPEIVPGAPQEEIIAAYRHEIDRLVAERGYQSVDVISMHPDNPKREELRAKFLDEHFHKEDEVRFFVDGRGLFTLHIDDKVYEIHCVKNDLISVPANTPHWFDMGEPPHFVAIRFFTEPEGWVAHFTGTDIAKQFPRYDPA

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT88.2
NLMSIM85.0
AACOMP89.6
Seqdif (SeqID)29.8 (WP_019399719.1)
Structdif (F-Target)13.0 (4qgm A)

ProtNLM

NameScore
1.13.11.540.113
ARD'0.106
Fe-ARD0.103
1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase0.101
Ni-ARD0.100
ARD0.099
Designed by MP, using an AMD MI250 GPU