MADMD

Prompt

4.1.1.48

Lyases. Carbon-carbon lyases. Carboxy-lyases. indole-3-glycerol-phosphate synthase.

AI Generated Sequence

257 AAs

MLDKIVAYKKREVALERKRVPLAELKAEARAAPPRGFAEALRAAGAGLSVIAEVKRASPSKGAIRADADPVAIARAYEGAGAAAISVLTERRYFGGSLADLRAVRAAVALPVLRKDFIVDPYQVHEARAHGADAVLLIVAALDDATLRELLAICRSLGMEVLVEVHTEAEAARALAAGARLIGVNARNLKTFEVDRATFARLAPLIPADVVKVAESGIAGPADVAYLARHGADAVLVGEALVRAADPGAAVAALLAG

Ligand/Cofactor

ATP

C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O)N

Validation Metrics

PLDDT	93.6
NLMSIM	90.0
AACOMP	82.3
Seqdif (SeqID)	37.1 (AZI59451.1)
Structdif (F-Target)	2.6 (3t55 A)

ProtNLM

Name	Score
IGPS	0.373
Indole-3-glycerol phosphate synthase	0.347
4.1.1.48	0.272
Indole-3-glycerol-phosphate synthase	0.003
Indole-3-glycerol phosphate synthase TrpC	0.002
Multifunctional fusion protein	0.000