MACBB

Prompt

3.1.6.4

Hydrolases. Acting on ester bonds. Sulfuric ester hydrolases. N-acetylgalactosamine-6-sulfatase.

AI Generated Sequence

288 AAs

MKKNIIFIMTDDHGWGQLGCYGNPLIETPNIDRLAAEGVRFTQAYVSNPLCAPSRAAILTGRYPHRNGVFTNNGRLGDQVGLLPDEITTLPGILKEAGYETAIVGKWHLGAVEGGFDHWSPQRGFDWFYGVLPGGHDYYPDALVYKDNRVVEIELDEKGYVTDTIYTDEALDFLDKRDDDKPFFLAYAFTAPHTPWQPPKKYHDLYRPDVLPPLPEMFDEEFGKRRMQAYMGAVRRVDDNVGRVLDALKESGLADNTIVVYTSDHGMYLGELGGRYKRLRDLLDYLKG

Ligand/Cofactor

N-acetyl-D-galactosamine 6-sulfate

CC(=O)NC1C(C(C(OC1O)COS(=O)(=O)O)O)O

Validation Metrics

PLDDT	86.1
NLMSIM	60.0
AACOMP	91.2
Seqdif (SeqID)	57.9 (UCH64258.1)
Structdif (F-Target)	10.4 (2qzu A)

ProtNLM

Name	Score
Sulfatase	0.582
Sulfatase-like hydrolase/transferase	0.200
Sulfatase domain-containing protein	0.095
Arylsulfatase	0.029
DUF229 domain-containing protein	0.021
Arylsulfatase A	0.014