MA99A

Prompt

3.5.2.9

Hydrolases. Acting on carbon-nitrogen bonds, other than peptide bonds. In cyclic amides. 5-oxoprolinase (ATP-hydrolyzing).

AI Generated Sequence

500 AAs

MKYDIGIDTGGTFTDIVVAKPDGKLIRTHKLLSTPDQYGDAVLEGIREILGLEKGEIPVEKIGSVKMGTTVATNALLERKGEKTALLITKGFRDVLEIAYQNRPKIFDLKIIKPELLYEKVIEIDERITADGTVIEKLDEEKVRKELQEKFDKGFESLAINFMHGYKYNAHELKVKEIAKEIFPFQVSVSHEVSPLIKLVERGDTAVNDAYLSPILRRYVNQMSEKLGRGANVVFMQSGGGLKEVDKFSGFKAILGGPAGGVVYGIEKTFPENFEKVIGGFDMGGSTDVTAYAGGSFERVFDTKAGVRLQGPSAGHVTVAAGGGGSLTFDNTLLVVGPESAGANPGPFCYKGGGPLDVTDANVMFGKLIPDHFPKIVGKENDQELVDVAVREKFAELAKQIEEKGTDHRFTLPDIGAGFLQIAVNAMANGIKKISVQARGDVTNYALVGFGGAGGQHVCKVADSLDMKTVFLHPASGVLSAMGIGLADLYVEKTGEEKIV

Ligand/Cofactor

ATP

C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O)N

Validation Metrics

PLDDT	85.7
NLMSIM	70.0
AACOMP	91.3
Seqdif (SeqID)	39.1 (WP_296606179.1)
Structdif (F-Target)	14.1 (5l9w b)

ProtNLM

Name	Score
5-oxoprolinase	0.626
3.5.2.9	0.101
5-oxoprolinase (ATP-hydrolysing)	0.066
5-oxoprolinase (ATP-hydrolyzing)	0.035
Hydantoinase/oxoprolinase	0.033
Hydantoinase/oxoprolinase family protein	0.020