M9YP8

Prompt

1.2.1.46

Oxidoreductases. Acting on the aldehyde or oxo group of donors. With NAD(+) or NADP(+) as acceptor. formaldehyde dehydrogenase.

AI Generated Sequence

442 AAs

MSGNRAVAYLGPGKVEVEEIDYPPEKKEIEHGVILKVVSTNICGSDQHMVRGRTTAPAGLVLGHEITGEVVEVGPDVENLKVGDLVSVPFNVACGRCRTCKEGQTGICLNVNPDRPGGAYGYVDMGGWVGGQAEYVMVPYADFNLLKIPDRDKAMEKIRDLTCLSDILPTGFHGAVTAGVGVGSTVYIAGAGPVGLAAAASARLLGAAVVIVGDVNVARLAQAKSQGFETVDLSKDTPLHEQIATLLGEPVDCAAVDAVGFEARGHGHGSKHEAPATVLNSLMDVTRAGGAIGIPGLYVTGDPGAVDAAAAKGSLSIRFGLGWAKSHSFHTGQTPVMKYNRALMQAIMHDRANIAEAIGATVISLDEAPRGYAEFDAGAAKKFVIDPHGGLFAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	83.6
NLMSIM	70.0
AACOMP	85.0
Seqdif (SeqID)	16.2 (HLD67884.1)
Structdif (F-Target)	4.2 (4jlw D)

ProtNLM

Name	Score
Formaldehyde dehydrogenase, glutathione-independent	0.442
Glutathione-independent formaldehyde dehydrogenase	0.231
1.2.1.46	0.169
Zinc-containing alcohol dehydrogenase super protein	0.014
Aldehyde dismutase	0.011
Aldehyde dismutase 1	0.010