M9VUI

Prompt

1.2.1.30

Oxidoreductases. Acting on the aldehyde or oxo group of donors. With NAD(+) or NADP(+) as acceptor. carboxylate reductase (NADP(+)).

AI Generated Sequence

495 AAs

MTEEVVREVRERLGGRLDAMATGSAPLSAELGEFVERLGVPLVEGYGSTEAGGVVVRGFGVDVDAYTVIDLAAARLGAVAVPLQTALPAEQLPAILAETEPRVLAADAAHLDAAVAALAAGPAARRLVVFDHRARVDAHRAAVAAVEAALAAGRALPAPLRYAPGDPDALALLYTSGSTGTPKGAMYPERLVADWWRGRGDAFGAGAPSVTLNFMPLSHVAGRDLLYGTLLAGGTGYFAAKSDLSTLFEDLRLVRPTELLAVPRVCDMFRRYLAAQVDRTVPDGELAARVRAELAARLGGRRLDALATGSAPLSAELGRFVEAVLGLPLHEYGSTTEAGQVVRHPVVDYKLTDVPELGYFRTDKPHPRGELLVKTDNMFPGYYKRPDVTAEVFADGWYRTGDVMAELGPDRLVYVDRRNNVLKLSQGEFVAPLALEAVFGASPLVRQIFVYGSAQRPYLLAVVVPTDAALAAAGRAGLTHYNMVHYVPRAAAAAG

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	73.2
NLMSIM	60.0
AACOMP	87.6
Seqdif (SeqID)	45.4 (STZ73761.1)
Structdif (F-Target)	23.1 (3cw8 X)

ProtNLM

Name	Score
Oxidoreductase	0.204
Carboxylic acid reductase	0.123
Fatty acid CoA ligase FadD9	0.113
Fatty-acid-CoA ligase FadD9	0.056
AMP-binding protein	0.054
Long-chain fatty acid--CoA ligase	0.044