M9VIF

Prompt

1.13.11.52

Oxidoreductases. Acting on single donors with incorporation of molecular oxygen (oxygenases). The oxygen incorporated need not be derived from O2. With incorporation of two atoms of oxygen. indoleamine 2,3-dioxygenase.

AI Generated Sequence

371 AAs

MSEIPVIDLSSLSSGDPAARDAIAAEIARACREWGFFQVKGHGIDEALIDRVFAASRAFFALPEAEKARYAIDPSGAHRGYETPGGERLAAGKPLDWKESFHIGYEVPLGDPYSAPLPGNEIWPEEMPGFRETMAAYYAAMEALGVRLLRALAEALGLEEDFFDAWCDDGNSILRLIHYPPQCAPPDGRARAGAHTDYGCLTLLLQDQVGGLQVLHRDGEWIDAPPLPGALVVNVGDMLQRWTNDRYKSTVHRVIRNPRGERRYSIAFFLHPRADAVIEPLPECVDAENPARYEPITAGEYLHGRLKATEGKRKPRLEAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	91.2
NLMSIM	70.0
AACOMP	82.8
Seqdif (SeqID)	47.6 (RPH46830.1)
Structdif (F-Target)	7.7 (3oox B)

ProtNLM

Name	Score
Fe2OG dioxygenase domain-containing protein	0.273
2-oxoglutarate-dependent dioxygenase	0.055
Oxidoreductase	0.033
2OG-Fe(II) oxygenase	0.022
1.13.12.19	0.020
Iron/ascorbate oxidoreductase DDB_G0283291	0.019