M9UOU

Prompt

1.14.19.26

Oxidoreductases. Acting on paired donors, with incorporation or reduction of molecular oxygen. The oxygen incorporated need not be derived from O2. With oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water. acyl-[acyl-carrier-protein] 6-desaturase.

AI Generated Sequence

297 AAs
MAQKPVTNALTLELEPVAEENLRRHLLTEEDWYAHDYVPFNQGENFGFLGGKDWDPGQSVLPKGITDACEIVLITKDNLAGYHRELVEHFILEDKWGRWLGRWTAEEHLHAIALRNYLVVTREVDPVANEDVRVQHVMKGYRADKYHSQMIETVYMAFQERAHTVFSRNTRQKIEDPVLAKMLGRIAKDEERHEMFIRNLVGHCLEYTRDETIQAIADRVEANFDMVGGILDFREKVQKIAKAGIYDPRAQDEVIRPVLKKWGIFEREDLPGFAGEKARQELAEFLEKLEKKRIETA

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT84.9
NLMSIM70.0
AACOMP91.4
Seqdif (SeqID)30.3 (WP_283633877.1)
Structdif (F-Target)12.5 (4v0j F)

ProtNLM

NameScore
Acyl-ACP desaturase0.639
1.14.19.20.067
Fatty acid desaturase0.067
1.14.19.-0.066
Acyl-[acyl-carrier-protein] desaturase desA10.045
Acyl-[acyl-carrier-protein] desaturase0.022
Designed by MP, using an AMD MI250 GPU