M9U2Z

Prompt

1.1.1.157

Oxidoreductases. Acting on the CH-OH group of donors. With NAD(+) or NADP(+) as acceptor. 3-hydroxybutyryl-CoA dehydrogenase.

AI Generated Sequence

500 AAs

MSEIKNVAVIGAGQMGNGIAHVCALAGLNVTLYDVSQERLDKGLATINKNLDRQVSKGKITEAEANAALSRITTSTNLADVADADLVIEAVTENEEVKHKIFKQLCPVLKPHTILASNTSSISITRLAASTDRPERFIGIHFMNPVPVMQLVELIRGIATSDETFETVKAFVEKLGKTPTVANDFPGFVVNRILMPMINEAVYTLYEGVASVEAIDTVMKLGANHPMGPLQLADFIGLDTCLSIMNVLHEGLGDSKYRPCPLLVKYVEAGWLGRKTGRGFYDYSGEDYVPTRSRRDRYLELALRCRKGKLSEEQAKALVEGLKGIIGGIEKDLKKLKELGLKLEELKKLKEELKKLKEELKKLEEELKKLEEELKKLEEELKKLEEELKKLEEELKKLEEELKKLEEELKKLEEELKKLEEELKKLEEELKKLEEELKKLEEELKKLEEELKKLEEELKKLEEELKKLEEELKKLEEELKKLEEELKKLEEELKKLKKKK

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	87.7
NLMSIM	90.0
AACOMP	82.1
Seqdif (SeqID)	25.3 (WP_188253548.1)
Structdif (F-Target)	1.7 (4r1n A)

ProtNLM

Name	Score
3-hydroxybutyryl-CoA dehydrogenase	0.537
1.1.1.157	0.368
3-hydroxyacyl-CoA dehydrogenase	0.066
1.1.1.35	0.009
4.2.1.17	0.002
3-hydroxyacyl-CoA dehydrogenase/enoyl-CoA hydratase family protein	0.002