M9FQ2

Prompt

1.2.1.12

Oxidoreductases. Acting on the aldehyde or oxo group of donors. With NAD(+) or NADP(+) as acceptor. glyceraldehyde-3-phosphate dehydrogenase (phosphorylating).

AI Generated Sequence

335 AAs

MTIKVAINGFGRIGRLVFRAALERGDIEIVAINDLIDPDYMAYMLKYDSTHGRFNGTVEVKDGNLVVNGKTIRVTAEKDPADLKWGEVGADYVVESTGLFLTKETAQKHITAGAKKVVMSAPSKDAPMFVCGVNHDKYDKTQTIVSNASCTTNCLAPLAKVLNDKFGIVEGLMTTVHATTATQKTVDGPSAKDWRGGRGASQNIIPSSTGAAKAVGKVIPELNGKLTGMSFRVPTPNVSVVDLTVRLEKPASYDEIKAAIKAASEGEMKGVLGYTEDDVVSTDFNGEARTSIFDAKAGIALNDKFVKLVSWYDNEWGYSNKVLDLIAHIAKVDGK

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	88.6
NLMSIM	70.0
AACOMP	91.5
Seqdif (SeqID)	13.3 (WP_088222067.1)
Structdif (F-Target)	3.6 (7xzg B)

ProtNLM

Name	Score
Glyceraldehyde-3-phosphate dehydrogenase	0.516
1.2.1.-	0.450
1.2.1.12	0.015
Glyceraldehyde-3-phosphate dehydrogenase A	0.010
Type I glyceraldehyde-3-phosphate dehydrogenase	0.002
NAD-dependent glyceraldehyde-3-phosphate dehydrogenase	0.001