M98TW

Prompt

6.3.5.2

Ligases. Forming carbon-nitrogen bonds. Carbon--nitrogen ligases.with glutamine as amido-N-donor. GMP synthase (glutamine-hydrolyzing).

AI Generated Sequence

519 AAs

MTQTIHPDRVLIVDFGSQVTQLIARRVREAGVYCEIVPFQSVDEGFIRLQPKGVILSGGPASTVLEGSPRAPQAVFDLGVPVLGICYGQQTMCMQLGGKVESGDHREFGRAFLEVKKDCRLFEGLWEGEERQVWMSHGDRVTKMPEGFKVIGTSPNAPFAIFADEKRKYYAVQFHPEVVHTPDGKKLLENFVHRIAGLKGDWTMRAYREQAVEAIREQVGDKKVICGLSGGVDSSVAALLIHEAIGDQLTCIFVDHGLMRLGEAEEVVNMFREHYNLPLIHVDAEDLFLGKLEGVSDPEKKRKIIGRLFIEVFEEHAKKLGGADFLGQGTLYPDVIESVSFTGGPSVTIKSHHNVGGLPERMNMKLVEPLRELFKDEVRALGRELGLPDSFIGRHPFPGPGLAIRCPGGITREKCEILREADAIYLDEIRKHGLYDEIWQAFAVLLPVKTVGVMGDGRTYDYVCALRAVTSVDGMTADFYHFDMEFLGRAATRIINEVRGINRVVYDVTSKPPGTIEWE

Ligand/Cofactor

ATP

C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O)N

Validation Metrics

PLDDT	84.3
NLMSIM	85.0
AACOMP	92.8
Seqdif (SeqID)	13.5 (WP_302751220.1)
Structdif (F-Target)	5.4 (7sbc D)

ProtNLM

Name	Score
GMP synthase [glutamine-hydrolyzing]	0.288
GMP synthetase	0.283
Glutamine amidotransferase	0.274
6.3.5.2	0.147
GMP synthase (glutamine-hydrolyzing)	0.004
Glutamine-hydrolyzing GMP synthase	0.001