M8PD0

Prompt

1.2.1.90

Oxidoreductases. Acting on the aldehyde or oxo group of donors. With NAD(+) or NADP(+) as acceptor. glyceraldehyde-3-phosphate dehydrogenase [NAD(P)(+)].

AI Generated Sequence

500 AAs

MTIKVAINGFGRIGRLVFRAALERPDVEVVAVNDPFIEPDYMAYMLKYDSTHGRFKGTVKVDGNNLIVNGKKIRVFAEKDPADIKWSEVGADYVVESTGVFLTTEKAQAHLTGGAKKVVISAPSADAPMFVCGVNEKTYKDDIKVVSNASCTTNCLAPLAKVINDNFTIVEGLMTTVHATTATQKTVDGPSAKDWRGGRGIAQNIIPSSTGAAKAVGKVIPSLNGKLTGMSFRVPTSDVSVVDLTVRLEKGASYDEIKAAMKAASEGPLKGILGYTEDDVVSTDFLGDTRTSIFDAKAGIALNDNFVKLVSWYDNEWGYSRRVLDLIAYISKVDGSKAGNVAVNTPDLGAASVAKAIKAELGKTLTSDRIPVEVANDVALVLNLKLEKTTTKEEVNAYLKDVALNSDLQKQIDYVVSNEVVSSDFVGSKYASIVDAEATIVQGDNAVVLYVWYDNEFGYSCQVIRVMQYMAGVEYTFMPKDVKGEAAAAAAAAAAAAAAA

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	74.5
NLMSIM	90.0
AACOMP	90.8
Seqdif (SeqID)	17.9 (KAF2734024.1)
Structdif (F-Target)	3.8 (3pym A)

ProtNLM

Name	Score
Glyceraldehyde-3-phosphate dehydrogenase	0.561
1.2.1.12	0.393
1.2.1.-	0.032
Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating)	0.002
Glyceraldehyde-3-phosphate dehydrogenase, cytosolic	0.001
Gp_dh_N domain-containing protein	0.001