M8N09

Prompt

1.2.1.38

Oxidoreductases. Acting on the aldehyde or oxo group of donors. With NAD(+) or NADP(+) as acceptor. N-acetyl-gamma-glutamyl-phosphate reductase.

AI Generated Sequence

399 AAs

MKKIGIIGASGYTGGELIRLLLNHPEVEITAVTSRSYAGEPVSTVHPSLRGITDLTFCNIDEIKDKVDLVFTALPHGVAMELVPELLDKGIKVIDLSADFRLKNPEIYEKWYKEEHAAPELLKEAVYGLPELNREEIKNAQLIANPGCYATAVQLGLAPLLKANLIDLDSIIIDAKSGSTGAGATPSTGSHFPERSENFKAYKVAGHRHLPEIEQELSYVAGKEIKVSFTPHLVPMNRGILSTVYANLKEGVSIEDLHKLYRDFYKDEPFVRIVPLGELPETKNVAGSNFCDIGFHVDERNNRLVIVSAIDNLMKGASGQAVQNMNLMLGYDETMGLDFIPLYPLEKKKEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	88.2
NLMSIM	85.0
AACOMP	85.2
Seqdif (SeqID)	40.2 (WP_078808754.1)
Structdif (F-Target)	3.3 (1xyg D)

ProtNLM

Name	Score
N-acetyl-glutamate semialdehyde dehydrogenase	0.225
N-acetyl-gamma-glutamyl-phosphate reductase	0.207
1.2.1.38	0.203
AGPR	0.188
NAGSA dehydrogenase	0.171
Acetylglutamate kinase	0.000