M8KE5

Prompt

1.8.4.7

Oxidoreductases. Acting on a sulfur group of donors. With a disulfide as acceptor. enzyme-thiol transhydrogenase (glutathione-disulfide).

AI Generated Sequence

523 AAs

MKLLLLLLLLPLLAAAAEDVLVLTKENFEDFIASHDLVLVEFYAPWCGHCKALAPAYEKAAATLKAKDSIKLAKVDCTVESDLCQEYGVRGYPTLKIFRGGDISKYTGGRKADGIVSYMIKQSGPAVSALTIDAAEKFTDSKDVVVIGFFKSDVKDSSEAFLKVASSLRDRYPFGVTSDADVAKEYGVKKPGIVLFKQFDEGKAVFDGKFDEDAIKAFIKTQALPLVGEVGPETYSGYIGAGIPLAYIFAEKSVSDRDELIPKLKPIAEKYKGKINFVAIDAKTFADHAGHLNLKTEEFPAFAIQTLEANKKFPQQSEDITADNIKEFVNDFLAGKLEPSLKSEPIPETWDGPVTVVVAKNYDEIVLNDSKDVLLEFYAPWCGHCKALAPKYDELGEKYKDHDKVVIAKMDATANDVPDAKIQGFPTIKFFAAGKKDTPITYSGNRTLEDLAKFLESGGHKAGLDVDEPLKEEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Ligand/Cofactor

glutathione disulfide

C(CC(=O)NC(CSSCC(C(=O)NCC(=O)O)NC(=O)CCC(C(=O)O)N)C(=O)NCC(=O)O)C(C(=O)O)N

Validation Metrics

PLDDT	92.1
NLMSIM	75.0
AACOMP	86.8
Seqdif (SeqID)	35.1 (XP_036580670.1)
Structdif (F-Target)	25.5 (4ekz A)

ProtNLM

Name	Score
Protein disulfide-isomerase	0.570
5.3.4.1	0.415
Peptide-methionine (S)-S-oxide reductase	0.001
Protein disulfide-isomerase A2	0.001
Multifunctional fusion protein	0.001
Protein disulfide isomerase	0.001