M8FXT

Prompt

3.5.2.10

Hydrolases. Acting on carbon-nitrogen bonds, other than peptide bonds. In cyclic amides. creatininase.

AI Generated Sequence

254 AAs
MKKIYLDELTWPEYEKVLKDDKIVILPVGATEQHGPHLPLGTDTLLAEKIAVEVAKKLDGVVAPALPYGYKQSKSGGGEHFPGTTSLTGATLIAYVKDIIGEFARHGFKKIVLVNGGHNNEFPLIEGAIELRIRELDDKVDAKIVSLLPWDFVSEETIKKFGHDGPFGVELAHAVLEPSLLMHLKAHNFVSLHKMKDHEAKLEPYPYVPFDWMKELTPSGVLASAKGASAEKGKLILDEVVDGIVKVLKEIFEL

Ligand/Cofactor

creatinine

CN1CC(=O)N=C1N

Validation Metrics

PLDDT86.9
NLMSIM90.0
AACOMP89.9
Seqdif (SeqID)51.7 (HCP02268.1)
Structdif (F-Target)8.0 (3a6j E)

ProtNLM

NameScore
Creatinine amidohydrolase0.296
Creatininase0.236
Creatininase family protein0.231
3.5.2.100.195
3.5.-.-0.011
Mycofactocin system creatinine amidohydrolase family protein MftE0.003
Designed by MP, using an AMD MI250 GPU