M8CJQ

Prompt

1.3.1.107

Oxidoreductases. Acting on the CH-CH group of donors. With NAD(+) or NADP(+) as acceptor. sanguinarine reductase.

AI Generated Sequence

369 AAs

MKILVTGATGFIGRHLVERLLERGHEVVGLLRNPDYVKNLEKAGVELKGVEFVEGDISDEESLKGVFKEHKPDIVFHLAAQIGVRYSIEDPNDYTETNVLGTINLLEACRKHKVKRFIYASSSSVYGVNKELPFSEEHDPRPSSPYAASKAAGEYIAHTYHNTYNLPTIVLRPFNVYGPWGRPDMAIFKFTKQILEGEPITIFGDGKQTRDFTYIDDVAEGIIKALDEKDIKGQTYNIGSGEKTTLYDLIELIEKELGKKEIKIPMPMRQGDVVTYYADISKAKELLGWKPETSLEEGLKRFVEWYRKYYKIEPGGKKIKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	94.5
NLMSIM	70.0
AACOMP	81.5
Seqdif (SeqID)	46.9 (MBN1792147.1)
Structdif (F-Target)	6.0 (4zrn B)

ProtNLM

Name	Score
NAD(P)-bd_dom domain-containing protein	0.292
NAD-dependent epimerase/dehydratase family protein	0.105
SDR family NAD(P)-dependent oxidoreductase	0.067
DTDP-glucose 4,6-dehydratase	0.062
UDP-glucose 4-epimerase	0.061
5.1.3.2	0.057