M86K2

Prompt

6.3.1.15

Ligases. Forming carbon-nitrogen bonds. Acid--ammonia (or amine) ligases.(amide synthases). 8-demethylnovobiocic acid synthase.

AI Generated Sequence

240 AAs
MADRALLLKRAAEIAREHGLDAVRVAFPDLNGVLRGKRFPAAYFLDSLAGGTGCGNYVLAWDIDMETVPGYALASWERGYGDFVMKPDLATLRRVPWLEGTALVLCDVLDEHDGTPVAASPRGILKRQIDRLAAMGWTAHAGTELEFFVFKESYEEAWRKGYRGLTPATPYINDYSIVQTTRVEPVLREIRRHMEAAGIPVENGKGECGPGQHEINLRYDEALEMADRHAIAKYGCKEIA

Ligand/Cofactor

ATP

C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O)N

Validation Metrics

PLDDT91.7
NLMSIM70.0
AACOMP92.3
Seqdif (SeqID)39.3 (WP_074991863.1)
Structdif (F-Target)17.0 (8tfk C)

ProtNLM

NameScore
Glutamine synthetase0.821
6.3.1.20.061
Gln-synt_C domain-containing protein0.033
Glutamine synthetase, catalytic domain protein0.010
Glutamine synthetase, type III0.009
Glutamine synthetase 20.006
Designed by MP, using an AMD MI250 GPU