M85XA

Prompt

1.3.1.21

Oxidoreductases. Acting on the CH-CH group of donors. With NAD(+) or NADP(+) as acceptor. 7-dehydrocholesterol reductase.

AI Generated Sequence

500 AAs

MAAHKQEKAAGRRRGYVLNKTDTQQQGWGRAWEVDWFSLAGIFFLMLFAPLIVYYFIMSCDQYQCSLTEPILDLLTGKTTLSDIWAKTPPTTTYRALGIYTVWVTFQVLLYMTIPDFCHKFLPGYVGGVQEGAVTPAGVVNKYEINGLQAWLITHLLWFANAYFLHWFSPTIIFDNWIPLLWCANILGYAVSTFAMIKGYFFPTNAKDCAFKNTGNFFYNYMMGIEFNPRIGKWFDFKLFFNGRPGIVAWTLINLSYFAKQQELYGQVTNSMILVNVLQGLYVLDFFWNEAWYLKTIDICHDHFGWYLAWGDCVWLPYLYTLQGLYLVYHPVQLSTAHAVGILLLGLLGYYIFRMTNHQKDLFRRTDGNCKIWGKKPKFIECSYTGDGKKYHSKLMTSGFWGVARHFNYTGDLMGSLAYCLACGGSHLLPYFYIIYMTILLTHRCIRDEHRCSSKYGKDWERYTAAVPYRLLPGIFGDRRRRRRRRRRRRRRRRRRRRRR

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	88.7
NLMSIM	95.0
AACOMP	90.9
Seqdif (SeqID)	14.3 (XP_009895752.1)
Structdif (F-Target)	4.4 (4quv A)

ProtNLM

Name	Score
7-dehydrocholesterol reductase	0.729
DHCR7 reductase	0.199
7-dehydrocholesterol reductase-like	0.022
DHCR7	0.008
7-dehydrocholesterol reductase-like protein	0.006
7-ketocholesterol reductase	0.004