M7ZE3

Prompt

3.1.4.8

Hydrolases. Acting on ester bonds. Phosphoric diester hydrolases. Transferred entry: 4.6.1.24.

AI Generated Sequence

499 AAs
MGLTPEEIDRLHLAGLLHDVGKIGIPDNILLKPGKLTPAEWEIMKQHPVYGYRILKSIGLLELPEIPICLQSHHERWDGSGYPNGLKGEEIPLEARIIAVADVFDAMTSDRPYKKAFTHEEALTILREGCGQHFDPRVVDAFLALQDPYLTIRRFCQLADGAYIRDHYAKQVNPYHNAVHAADVTQTMHCVLLKTPRLAHSITELEILALIFAAATHDIEHPGLTNSFLINTKTPLAILYNDRSVLENHHLSAAFGLLQDEPGNIFVNLSDEQRKLLRTIIESIVLATDMTKHFETLAKFRTMLKKEGHIDAAVARDLWHPYTIDDWMNNEEIYKALKEHYEKLGLTDVQTEICQQLLLKFIQVRENYRTDPYHNFRHSCDVTQAMFYLIMKCADIANPARPLELSKRWAERLSEEFFLQGDIEKELGLPVSPLMDRDKSTLAPKSQIGFIDFVVEPLFTAFADLCDKIPQMLHHLPENRQKWEELAKAEKEGLLPPEE

Ligand/Cofactor

cAMP

C1C2C(C(C(O2)N3C=NC4=C(N=CN=C43)N)O)OP(=O)(O1)O

Validation Metrics

PLDDT78.0
NLMSIM70.0
AACOMP92.7
Seqdif (SeqID)58.6 (XP_053631264.1)
Structdif (F-Target)13.7 (5vyd B)

ProtNLM

NameScore
Phosphodiesterase0.471
3.1.4.-0.419
3.1.4.520.034
HD domain-containing protein0.017
HD-GYP domain-containing protein0.014
3.1.4.170.011
Designed by MP, using an AMD MI250 GPU