M7DNI

Prompt

1.1.1.433

Oxidoreductases. Acting on the CH-OH group of donors. With NAD(+) or NADP(+) as acceptor. sulfoacetaldehyde reductase (NADH).

AI Generated Sequence

466 AAs

MKIGVIGLGNLGGEMALNLAKAGHEVTGYDITVEDVEPHTVFGAELADTPAAAAERSDVVTMPLRNPEQRENVVFGEDGVVEGIEAGETVVLNSTIDPVSYDELAEEIGGEVDGFMDAPVGGSGIGAKEGTLNAIVGGEELFERAKEPLLTMDEERVVLNGVGVVGGQTKGVNEMLAGLHNMALSEALDFNERIGLDTEVTLVDIAGGRLAPMSESLRSAHVEELFDEFGVEIKTGIMKDVADEGVELEDGTEIPTGMLVWTAGQAGALMGELGAEDQTGRVRLVEDTYLEVPGAEGVYAVGDVAAVDEETGRPVGTVAQVAQLGGYVAENIAAEMEGEEPLEPFEYKDLGSMAVIGRNTAVGGLGWVTLSGFIAWLWKRMGHLRFFLSENRKMVRVMYDWAVNYFTDREIRLIIPEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	74.0
NLMSIM	70.0
AACOMP	82.2
Seqdif (SeqID)	69.0 (MBF1070748.1)
Structdif (F-Target)	30.4 (3pef D)

ProtNLM

Name	Score
NAD(P)-dependent oxidoreductase	0.220
NAD(P)/FAD-dependent oxidoreductase	0.144
NAD(P)-binding protein	0.068
1.18.1.2	0.060
6-phosphogluconate dehydrogenase	0.059
NAD_binding_2 domain-containing protein	0.056