M73LA

Prompt

6.3.4.13

Ligases. Forming carbon-nitrogen bonds. Other carbon--nitrogen ligases. phosphoribosylamine--glycine ligase.

AI Generated Sequence

473 AAs

MKVLVIGSGGREHALAWKLAQSPLVTKVYVAPGNAGMAQEAECVNIAAGDIPGLVAFAKENKIDLTVVGPEAPLVLGIVDDFRARGIRTFGPSKAAAQLEGSKVFTKDFMAKYDIPTAAYERFTDAAPAKAYVEAQGAPIVIKADGLAAGKGVTVAMTLEEALAAVDDMFAGNAFGDAGAEVVVEDFLDGEEASFLCLVDGKTALPMATAQDHKRVGDGDTGPNTGGMGAYSPAPVMTEEVVARTMREIVLPTVRGMAAEGAPFSGVLFAGLMITADGPKLIEYNCRFGDPECQVLMMRLKSDLLVLLNACLDGTLDKVSAEWSDGAALTVVMAAKGYPGAYEKGTVIRGLDAAEGDGVEIFHAGTALKDGQVVANGGRVLNVTALGATVAEAQKRAYAAVDRIDWPGGFCRRDIGWRAVAREAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Ligand/Cofactor

ATP

C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O)N

Validation Metrics

PLDDT	94.0
NLMSIM	70.0
AACOMP	82.7
Seqdif (SeqID)	24.0 (WP_195175807.1)
Structdif (F-Target)	2.2 (2xd4 A)

ProtNLM

Name	Score
6.3.4.13	0.219
Glycinamide ribonucleotide synthetase	0.168
Phosphoribosylglycinamide synthetase	0.160
Phosphoribosylamine--glycine ligase	0.138
Phosphoribosylformylglycinamidine cyclo-ligase	0.083
GARS	0.048