M71HH

Prompt

1.1.1.193

Oxidoreductases. Acting on the CH-OH group of donors. With NAD(+) or NADP(+) as acceptor. 5-amino-6-(5-phosphoribosylamino)uracil reductase.

AI Generated Sequence

413 AAs

MTEQQYMALALELAQKGLGYTSPNPLVGAVIVKDGQIVGEGWHQRAGEPHAEVHALRQAGELARGATLYVTLEPCSHYGKTPPCADALIAAGVARVVAAMRDPNPLVAGKGIAMLRAAGIEVEVGLLEAEARALNEGFLKRMTTGLPFVTLKMAMSLDGKIATATGESQWITGAEARADVHRLRAEADAILVGIGTVLADDPALTVRLPEGGRQPVRIVLDSRLRTPLAARVLQGGAAPTLIATAAAADAAKRAALAAAGVEVLELPAGGGRLDLPALMAHLGERGINSLLVEAGGTLHGAFLAAGLVDKVAVYVAPKLIGGAGARPMVGGLGLATMADALRLKLVDREQVGDDLLLTGYLPAGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	88.6
NLMSIM	70.0
AACOMP	81.8
Seqdif (SeqID)	36.7 (KKM12961.1)
Structdif (F-Target)	6.8 (8dq9 B)

ProtNLM

Name	Score
HTP reductase	0.185
5-amino-6-(5-phosphoribosylamino)uracil reductase	0.132
DRAP deaminase	0.124
1.1.1.193	0.120
Diaminohydroxyphosphoribosylaminopyrimidine deaminase	0.115
3.5.4.26	0.111