M6O20

Prompt

1.1.1.18

Oxidoreductases. Acting on the CH-OH group of donors. With NAD(+) or NADP(+) as acceptor. inositol 2-dehydrogenase.

AI Generated Sequence

388 AAs

MTIRVGIFGAGRIGQVHAANIAAHPDAELVAVADPFHERAAALAEKYGAKVYTDVDAVLADPDVDAVLICSSTDTHAELIELAAKAGKHVFCEKPVDLSLERIKACLDVVEKSGVKLQIGFNRRFDPNFKALKARVEAGEIGEIELIRITSRDPEPPPVEYIKVSGGIFRDMTIHDFDMARWIMGEEVEEVFASGSCLVDPAIGEAGDVDTAVVTLRTANGAMCTIDNSRAAVYGYDQRIEVFGSKGMLQVGNDRPTTVSLWSEKGALKDKPQHFFLERYADAYAAEIAHFVDAVRNGEPTVVSGEDGLAQVALAEAAEKSFETGRPVKLDELLLGGGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	85.1
NLMSIM	90.0
AACOMP	83.8
Seqdif (SeqID)	41.2 (WP_232293080.1)
Structdif (F-Target)	6.2 (3ezy B)

ProtNLM

Name	Score
Inositol 2-dehydrogenase	0.566
1.1.1.18	0.244
Myo-inositol 2-dehydrogenase	0.062
Myo-inositol 2-dehydrogenase 1	0.019
Inositol 2-dehydrogenase 1	0.012
Myo-inositol dehydrogenase	0.012