M6IZ2

Prompt

1.1.1.79

Oxidoreductases. Acting on the CH-OH group of donors. With NAD(+) or NADP(+) as acceptor. glyoxylate reductase (NADP(+)).

AI Generated Sequence

326 AAs

MTDRPKVLVTRRLPDVVETRMRELFDVELNEIDRPMTREELTARLAGADALVPTVTDKIDAELLDLGAGLKLIANFGAGYDHIDLDAARARGILVTNTPDVLTEDTADMTLALILAVARRVGEGERVLREGNWAGWSPTWMLGRHVHGKRLGIVGMGRIGQAVARRARAFGMDVLYHNRSRLRPEVEAELGATYWESLDELLARSDFVSVNCPYTPETYHMINARRLAKMKPTAYLINTARGPVIDEDALVAALKEGRIRGAGLDVYEHEPNVDPALLALDNVVLLPHMGSATVETRIGMGEKVAVNIVKAAAGHEPPDRVLPRAV

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	97.8
NLMSIM	70.0
AACOMP	90.9
Seqdif (SeqID)	32.3 (WP_193172453.1)
Structdif (F-Target)	5.1 (2dbq A)

ProtNLM

Name	Score
D-glycerate dehydrogenase	0.368
Glyoxylate reductase	0.270
2-hydroxyacid dehydrogenase	0.149
1.1.1.26	0.035
Lactate dehydrogenase-like 2-hydroxyacid dehydrogenase	0.034
Lactate dehydrogenase	0.028